Cannabinoids and their medical applications

Understanding the Medical Applications of THC, CBD, and CBN

Medical Applications and Use Cases

THC (Tetrahydrocannabinol)

  1. Pain Relief: Effective for chronic pain relief but may cause euphoria and sedation. Starting dose: 2.5-5mg THC.
  2. Anxiety Reduction: May reduce anxiety at low doses but can exacerbate it at higher doses.
  3. Anti-Inflammation: Shows promise in reducing inflammation but is less studied than CBD.
  4. Sleep Aid: Often used for insomnia but may lead to grogginess upon waking.

CBD (Cannabidiol)

  1. Pain Relief: Effective for neuropathic pain, less psychoactive impact. Starting dose: 5-10mg CBD.
  2. Anxiety Reduction: Widely used for anxiety and PTSD.
  3. Anti-Inflammation: Proven efficacy for treating inflammation.
  4. Epilepsy Control: Proven effective for certain forms of epilepsy such as Dravet syndrome.

CBN (Cannabinol)

  1. Pain Relief: Less potent than THC and CBD but has potential. Starting dose: 2.5-5mg CBN.
  2. Sleep Aid: Known for its sedative effects.
  3. Anti-Inflammation: Some evidence supporting anti-inflammatory potential.
  4. Antibacterial: Exhibits antibacterial properties, especially against MRSA.

Comprehensive Comparison Table

AspectQuestions to AskTHCCBDCBN
Pain ReliefWhat type of pain do I have?Effective for chronic painEffective for neuropathic painLess potent but promising
Anxiety ReductionAm I prone to THC-induced anxiety?Dose-dependent effectsWidely used for anxietyNot well-studied
Anti-InflammationDo I have a gastrointestinal disorder?Promising but less studiedProven efficacySome evidence
Epilepsy ControlDo I have a form of drug-resistant epilepsy?Limited studiesEffective for Dravet syndromeNot well-studied
Sleep AidDo I have trouble falling asleep or staying asleepEffective but may cause grogginessLimited evidenceKnown for sedative effects
AntibacterialAm I looking for antibacterial properties?Limited evidenceLimited evidenceEffective against MRSA


  1. Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects. British Journal of Pharmacology, 163(7), 1344-1364.
  2. MacCallum, C. A., & Russo, E. B. (2018). Practical considerations in medical cannabis administration and dosing. European Journal of Internal Medicine, 49, 12-19.
  3. Whiting, P. F., Wolff, R. F., Deshpande, S., Di Nisio, M., Duffy, S., Hernandez, A. V., … & Schmidlkofer, S. (2015). Cannabinoids for medical use: A systematic review and meta-analysis. JAMA, 313(24), 2456-2473.
  4. Mechoulam, R., & Hanuš, L. (2002). Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects. Chemistry and physics of lipids, 121(1-2), 35-43.
  5. Appendino, G., Gibbons, S., Giana, A., Pagani, A., Grassi, G., Stavri, M., … & Rahman, M. M. (2008). Antibacterial cannabinoids from Cannabis sativa: a structure− activity study. Journal of Natural Products, 71(8), 1427-1430.

Medical Illnesses and Diagnoses for Caution

  • Cardiovascular Diseases
  • Psychotic Disorders
  • Liver Disorders

For specialized care for these conditions, consult Dr. Benjamin Caplan at CED Clinic.

📗 Note: The diagram’s a swig of soda; the book’s a sip of fine wine. Uncork it here 📗

Cover of The Doctor-Approved Cannabis Handbook featuring a green medical plus symbol
Unlock the world of medical cannabis with The Doctor-Approved Cannabis Handbook.

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