Emerging research in dermatology indicates that lesser-known cannabinoids, such as THCV, CBDV, CBC, CBM, and CBN, may offer therapeutic benefits for various skin conditions including psoriasis, eczema, and acne. This guide will delve into the scientific evidence surrounding the therapeutic promise of these minor cannabinoids in managing dermatological conditions.
Potential Therapeutic Applications of Minor Cannabinoids
Chart: Minor Cannabinoids and Their Utility in Dermatology
|Cannabinoid||Skin Conditions Addressed||Potential Benefits||Known Risks and Limitations|
|THCV||Acne||Regulates sebum production, exhibits anti-inflammatory and antibacterial properties||Limited Clinical Trials|
|CBDV||Atopic Dermatitis, Acne||Anti-inflammatory, Antioxidant||Limited Clinical Trials|
|CBC||Acne, Psoriasis, Atopic Dermatitis||Anti-inflammatory, Antioxidant||Limited Clinical Trials|
|CBM||Under investigation||Anti-inflammatory||Limited Clinical Trials|
|CBN||Under investigation||Potential anti-inflammatory||Limited Clinical Trials|
Mechanism of Action: The Endocannabinoid System
The effects of these minor cannabinoids are believed to be mediated by the body’s endocannabinoid system, a crucial regulatory mechanism responsible for maintaining the health and proper functioning of various biological processes, including skin functions like immune response, cell proliferation, differentiation, and suppression of inflammation (Kwiecień & Kowalczuk, 2021).
Precautions and Risks
While these minor cannabinoids exhibit promising therapeutic properties, more research is needed to confirm their effectiveness and safety. Issues related to product quality, regulation, legality, and potential health risks should be carefully considered (Kwiecień & Kowalczuk, 2021). For expert advice on cannabinoid use in dermatological conditions, consult Dr. Caplan at CED Clinic.
- Kwiecień, E., & Kowalczuk, D. (2021). Minor cannabinoids: Therapeutic promise in the management of dermatological diseases. Molecules.
- Atalay, S., Jarocka-Karpowicz, I., & Skrzydlewska, E. (2019). Antioxidative and Anti-Inflammatory Properties of Cannabidiol. Antioxidants.
- Ali, A., & Akhtar, N. (2015). The safety and efficacy of 3% Cannabis seeds extract cream for reduction of human cheek skin sebum and erythema content. Pakistan Journal of Pharmaceutical Sciences.
- Pellati, F., Borgonetti, V., Brighenti, V., Biagi, M., Benvenuti, S., & Corsi, L. (2018). Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer. BioMed Research International.
📗 Note: The diagram you see here is based on principles discussed in greater depth in “The Doctor-Approved Cannabis Handbook.” Enhance your knowledge by purchasing the book directly through this link 📗